Creative Biolabs has developed a series of antibody tools targeting key proteins in neuroscience and muscle genetics, aiming to facilitate research into neurodegenerative diseases, movement disorders, and muscle function. The new products include antibodies against GRID2, tyrosine hydroxylase (TH), and ACTN3, each playing a critical role in their respective fields.
GRID2, a gene encoding the delta2 glutamate receptor, is essential for cerebellar development and synaptic transmission. Mutations in GRID2 have been linked to cerebellar ataxia and learning deficits. Creative Biolabs now offers Rabbit Anti-GRID2 Recombinant Antibody and Mouse Anti-GRID2 Recombinant Antibody, applicable in ELISA, flow cytometry, Western blotting, and immunohistochemistry. These tools enable researchers to study synaptic protein dynamics with high specificity. A neuroscientist at Creative Biolabs stated, "GRID2 has emerged as a key point for understanding both cerebellar development and mechanism learning. Our antibody tool sets aim to assist researchers in generating clearer molecular maps within cell and animal model systems."
Tyrosine hydroxylase (TH) is the rate-limiting enzyme in catecholamine synthesis, converting L-tyrosine to L-DOPA, a precursor for dopamine, norepinephrine, and epinephrine. TH levels are a key marker in Parkinson's disease research, reflecting dopaminergic neuron function. Creative Biolabs' Mouse Anti-Tyrosine Hydroxylase Recombinant Antibody (AV1) is optimized for Western blot and immunohistochemistry, aiding in the detection of molecular changes in neurotransmitter pathways. The scientist noted, "TH research is critical to understanding underlying mechanisms related to Parkinson's disease but also to the development of new neuroprotective strategies."
ACTN3 encodes α-actinin-3, a protein essential for fast-twitch muscle fiber function. Creative Biolabs provides Mouse Anti-ACTN3 Recombinant Antibody (applications: IHC, WB) and Rabbit Anti-ACTN3 Recombinant Antibody (applications: WB, IH, IC, Flow) with high specificity and cross-species reactivity. These tools support studies in sports genetics, muscle disorders, and personalized training research.
Creative Biolabs is dedicated to providing customized antibody solutions and professional technical support to researchers worldwide, covering antibody development, large-scale production, and protocol optimization.
